DALLAS, May 7, 2024 /PRNewswire/ -- Nanoscope Therapeutics Inc., a late-stage clinical biotechnology company developing gene therapies for retinal degenerative diseases, today announced that its viral and laser-delivered Multi-Characteristic Opsin (MCO) gene therapy platforms will be featured in multiple presentations at the 2024 ASGCT Annual Meeting and the Retina World Congress, being held in Baltimore, Maryland and Fort Lauderdale, Florida, respectively, in May. Details are as follows: 2024 American Society of Gene + Cell Therapy (ASGCT) Annual Meeting
Abstract Title: Longitudinal Analysis of BCVA and Near-Field Object Recognition in Low- or High-Dose MCO-010 Mutation Agnostic Optogenetic Therapy for Retinitis Pigmentosa: 12-Month Results from a Phase 2b/3 Randomized, Sham-Controlled, Patient- and Assessor-Masked Clinical Trial (RESTORE) Abstract/Poster Number: 917
Session Type: Poster Session
Session Title: Wednesday Posters: Gene Therapy Trials - In Vivo Modification
Session Date: May 8, 2024
Session Time: 12:00 – 7:00 p.m. ET
Presenter: Samuel Barone, MD, Chief Medical Officer
Presentation Title: Non-Viral Targeted Laser Delivery of Multi-Characteristic Opsin Genes for Treatment of Geographic Atrophy Session Type: Oral Abstract Session
Session Title: Nonviral Approaches for Therapeutic Applications
Session Date: May 11, 2024
Session Time: 11:15 – 11:30 a.m. ET
Presenter: Samarendra Mohanty, PhD, President & Chief Scientific Officer
Retina World Congress 2024
Session Title: Gene Therapy, Pharmacotherapy and Optogenetics for IRD
Session Date: May 9, 2024
Session Time: 9:05 – 9:35 a.m. ET
Location: Fort Lauderdale Marriott Harbor Beach Hotel
Presenter: Samarendra Mohanty, PhD, Chief Scientific Officer
Presentation Title: Longitudinal BCVA and Safety Analysis of Mutation-Agnostic MCO-010 Optogenetic Therapy For Retinitis Pigmentosa: Patient Case From A Phase 2b Randomized, Sham-Controlled, Patient- And Assessor-Masked Clinical Trial (RESTORE) Session Title: Gene and Cell Therapy
Session Date: May 10, 2024
Session Time: 2:21 – 2:26 p.m. ET
Location: Fort Lauderdale Marriott Harbor Beach Hotel
Dr. Kay will detail the statistically significant and clinically meaningful improvements in visual acuity observed longitudinally for an individual with advanced retinitis pigmentosa (RP) treated with MCO-010 in the RESTORE trial. Nanoscope Therapeutics is developing gene-agnostic, sight-restoring optogenetic therapies for the millions of patients blinded by inherited retinal diseases, for which no cure exists. The company's lead asset, MCO-010, recently announced the 100-week data from the RESTORE Phase 2b multicenter, randomized, double-masked, sham-controlled clinical trial in the U.S. for RP (NCT04945772). The company has also recently completed the Phase 2 STARLIGHT trial of MCO-010 therapy in patients with Stargardt disease (NCT05417126). MCO-010 has received FDA fast-track designations and FDA orphan drug designations for both RP and Stargardt disease. Preclinical assets include non-viral laser-delivered MCO-020 gene therapy for GA due to AMDAMD. SOURCE Nanoscope Therapeutics